Solving an MHC allele–specific bias in the reported immunopeptidome
نویسندگان
چکیده
منابع مشابه
The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation
Self/non-self discrimination is a fundamental requirement of life. Endogenous peptides presented by major histocompatibility complex class I (MHC I) molecules represent the essence of self for CD8 T lymphocytes. These MHC I peptides (MIPs) are collectively referred to as the immunopeptidome. From a systems-level perspective, very little is known about the origin, composition and plasticity of t...
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ژورنال
عنوان ژورنال: JCI Insight
سال: 2020
ISSN: 2379-3708
DOI: 10.1172/jci.insight.141264